The problems of drug-resistant pathogenic bacteria. R factors: biochemical mechanisms of resistance to aminoglycoside antibiotics.

Acetylesterase/metabolism Adenosine Triphosphate/metabolism Amines/metabolism,pharmacology Anti-Bacterial Agents/metabolism,pharmacology Bacteria/drug effects Carbon Isotopes Chemical Phenomena Chemistry Coenzyme A/metabolism Drug Resistance, Microbial Escherichia coli/drug effects,enzymology Genetics, Microbial Glycosides/metabolism,pharmacology Ligases/metabolism Phosphorus Isotopes Phosphotransferases/metabolism

Amines Anti-Bacterial Agents Carbon Isotopes Glycosides Phosphorus Isotopes Adenosine Triphosphate Phosphotransferases Acetylesterase Ligases Coenzyme A