Repair of alkylated bacteriophage T4 deoxyribonucleic acid by a mechanism involving polynucleotide ligase.

Journal of virology ·Vol. 7 ·No. 3 ·1971-03-00 ·Pages 407-8

Baldy MW, Strom B, Bernstein H

Abstract

Methyl methanesulfate-induced lesions in bacteriophage T4 are repaired primarily by a mechanism involving polynucleotide ligase. Apparently, other recombinational and ultraviolet repair functions aren't involved.

MeSH Terms

Adsorption Alkanes/pharmacology Coliphages/drug effects,enzymology,growth & development,radiation effects DNA Nucleotidyltransferases/metabolism DNA Replication DNA, Viral/metabolism Drug Resistance, Microbial Escherichia coli Genes Genetics, Microbial Ligases/metabolism Mutation Recombination, Genetic Temperature Ultraviolet Rays

Chemicals

Alkanes DNA, Viral DNA Nucleotidyltransferases Ligases

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Baldy M W

Strom B

Bernstein H

References (6)

6 references, click to expand

Effects of some chemical mutagens and carcinogens on nucleic acids.
Prog Nucleic Acid Res Mol Biol. 1966;5:89-131 PMID: 5337700
Molecular mechanisms of genetic recombination in bacteriophage. VI. A mutant defective in the joining of DNA molecules.
J Mol Biol. 1966 Nov 14;21(2):247-53 PMID: 4291402
Repair and recombination in phage T4. I. Genes affecting recombination.
Cold Spring Harb Symp Quant Biol. 1968;33:325-31 PMID: 4891972
Mechanism of repair of DNA in bacteriophage. I. Excision of pyrimidine dimers from ultraviolet-irradiated DNA by an extract of T4-infected cells.
J Mol Biol. 1970 Jan 28;47(2):231-42 PMID: 4907728
The UV sensitivity of some early-function temperature-sensitive mutants of phage T4.
Virology. 1970 Feb;40(2):272-87 PMID: 4909413
Mutants of phage T4 with increased sensitivity to ultraviolet.
Virology. 1963 Jan;19:66-71 PMID: 13952844

Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.7.3.407-408.1971

Published

1971-03-00

Pages

407-8

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC356131

Subset

External Links

PubMed source DOI: 10.1128/JVI.7.3.407-408.1971 PMC Full Text View journal details

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Repair of alkylated bacteriophage T4 deoxyribonucleic acid by a mechanism involving polynucleotide ligase.

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