Pepsin digestion of human G-myeloma proteins of different subclasses. I. The characteristic features of pepsin cleavage as a function of time.

Clinical and experimental immunology ·Vol. 7 ·No. 5 ·1970-11-00 ·Pages 603-25

Turner MW, Bennich HH, Natvig JB

Abstract

暂无摘要

MeSH Terms

Bence Jones Protein/analysis Chromatography, DEAE-Cellulose Chromatography, Gel Electrophoresis Gels Humans Immunoelectrophoresis Immunoglobulin G/analysis Immunoglobulins/analysis Pepsin A Peptides/analysis Starch Time Factors

Chemicals

Gels Immunoglobulin G Immunoglobulins Peptides Starch Bence Jones Protein Pepsin A

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Turner M W

Bennich H H

Natvig J B

References (16)

16 references, click to expand

Role of cysteine in the production of Fc and F'c sub-components of gamma-G myeloma globulins.
Nature. 1965 Sep 4;207(5001):1092-3 PMID: 4160050
Pepsin digestion of human G-myeloma proteins of different subclasses. II. Immunochemical investigations of the products of peptic digestion.
Clin Exp Immunol. 1970 Nov;7(5):627-40 PMID: 4992782
Structural studies of immunoglobulins. 3. Susceptibility of human gamma G globulins to peptic hydrolysis and papain sensitivity of F(ab')2 fragments.
Immunochemistry. 1969 May;6(3):473-9 PMID: 4891904
Isolation and antigenic characterization of pFc' fragments from six genetically different human G myeloma proteins.
FEBS Lett. 1970 Feb 16;6(3):193-197 PMID: 11947372
Variations among gamma-globulins at the antigenic site revealed by pepsin digestion.
J Clin Invest. 1966 May;45(5):714-23 PMID: 5327482
Products of the peptic digestion of human gamma-G-immunoglobulin.
Biochemistry. 1967 Jan;6(1):127-34 PMID: 4166154
The papain susceptibility of IgG myeloma proteins of different heavy chain subclasses.
Immunochemistry. 1970 Jan;7(1):1-6 PMID: 5416392
Studies on structural units of the gamma-globulins.
J Exp Med. 1961 May 1;113:861-84 PMID: 13725659
Structural studies of immunoglobulin G.
Nature. 1969 Jan 11;221(5176):145-8 PMID: 5782707
PREPARATION OF ANTISERA SPECIFIC FOR 6.6 S GAMMA-GLOBULINS, BETA 2A-GLOBULINS, GAMMA-1.-MACROGLOBULINS, AND FOR TYPE I AND II COMMON GAMMA-GLOBULIN DETERMINANTS.
J Immunol. 1963 Oct;91:484-97 PMID: 14082035
Relationship between the papain sensitivity of human gammaG immunoglobulins and their heavy chain subclass.
Nature. 1968 Aug 10;219(5154):646-9 PMID: 4174290
The release of Fe' and pFc' fragments from human immunoglobulin G following enzymic digestion: a time study.
Biochim Biophys Acta. 1969 Mar;175(2):388-95 PMID: 4976454
Simple method of subtyping human G-myeloma proteins based on sensitivity to pepsin digestion.
Nature. 1970 Feb 28;225(5235):853-5 PMID: 4905901
Subfragments from the Fc fragment of human immunoglobulin G. Isolation and physicochemical charaterization.
Biochem J. 1968 Mar;107(2):171-8 PMID: 4171016
[Method permitting the combined study of the electrophoretic and the immunochemical properties of protein mixtures; application to blood serum].
Biochim Biophys Acta. 1953 Jan;10(1):193-4 PMID: 13041735
Genetically determined antigen of the Ne subgroup of gamma-globulin: detection by precipitin analysis.
Science. 1966 Nov 25;154(3752):1041-3 PMID: 4162154

Article Info

Journal

Clinical and experimental immunology

Abbr.

Clin Exp Immunol

ISSN

0009-9104

Published

1970-11-00

Pages

603-25

Language

English

Region

England

NLM ID

0057202

PMCID

PMC1712889

Subset

External Links

PubMed source PMC Full Text View journal details

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Pepsin digestion of human G-myeloma proteins of different subclasses. I. The characteristic features of pepsin cleavage as a function of time.

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