Fitness of an Escherichia coli mutator gene.

Science (New York, N.Y.) ·Vol. 169 ·No. 3946 ·1970-08-14 ·Pages 686-8

Gibson TC, Scheppe ML, Cox EC

Abstract

Competition experiments between Escherichia coli mutT1 and mut(+) populations show that the mutator gene confers selective advantage on the strain that carries it. The observed increase in fitness varies, with an average increase in mutator growth rate of 1.4 percent when mutator and wild-type strains are grown together in chemostats.

MeSH Terms

DNA Replication Escherichia coli/metabolism Genes Genetics, Microbial Lactose/metabolism Mutation Selection, Genetic

Chemicals

Lactose

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Gibson T C

Scheppe M L

Cox E C

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.169.3946.686

Published

1970-08-14

Pages

686-8

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.169.3946.686 View journal details

Analysis Services

Fitness of an Escherichia coli mutator gene.

Contact

WeChat Official Account