[Ultrastructural events associated with the action of tolbutamide and glybenclamide on pancreatic B-cells in vivo and in vitro].

Animals Blood Glucose/analysis Cell Membrane Cell Membrane Permeability Cytoplasm Endoplasmic Reticulum/metabolism Golgi Apparatus/metabolism Hypoglycemic Agents/pharmacology In Vitro Techniques Insulin/analysis,biosynthesis,blood,metabolism Insulin Secretion Islets of Langerhans/analysis,cytology,drug effects,immunology Male Microscopy, Electron Mitochondria/metabolism Oxygen Consumption Protein Biosynthesis Rats Solubility Sulfonamides/pharmacology Tolbutamide/pharmacology

Blood Glucose Hypoglycemic Agents Insulin Sulfonamides Tolbutamide