Mutator gene studies in Escherichia coli.

Journal of bacteriology ·Vol. 100 ·No. 1 ·1969-10-00 ·Pages 390-7

Cox EC, Yanofsky C

Abstract

An Escherichia coli mutator gene, mutT, has been shown by P1-mediated crosses to map between the leucine and azide loci. The mutT1 and azi-r alleles cotransduce with a frequency of >92%. In mutT1/mutT(+) merodiploids, the mutT1 phenotype is recessive; in mutT1/F'trp or mutT1/F'lac merodiploids, the mutT1 allele has a trans effect. The gene can mutate lambda and T7 phage but not T1, T3, T4, T5, and S13.

MeSH Terms

Chromosome Mapping Coliphages Escherichia coli Genes Genes, Recessive Genetics, Microbial Molecular Biology Mutation Phenotype Transduction, Genetic

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Cox E C

Yanofsky C

References (19)

19 references, click to expand

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Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.100.1.390-397.1969

Published

1969-10-00

Pages

390-7

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC315405

Subset

External Links

PubMed source DOI: 10.1128/jb.100.1.390-397.1969 PMC Full Text View journal details

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