Antitumor activity and other biologic properties of L-asparaginase (NSC-109229)-a review.

Animals Asparaginase/isolation & purification,metabolism,pharmacology,therapeutic use Carcinosarcoma/drug therapy Dogs Escherichia coli/analysis Guinea Pigs Humans Leukemia/drug therapy Leukemia, Experimental/drug therapy Leukemia, Lymphoid/drug therapy Leukemia, Myeloid, Acute/drug therapy Ligases/metabolism Lymphoma/drug therapy Lymphoma, Non-Hodgkin/drug therapy Mice Neoplasm Transplantation Neoplasms, Experimental/enzymology Rats Sarcoma/drug therapy Tritium Uridine/metabolism Valine/metabolism

Tritium Asparaginase Ligases Valine Uridine