Home LiteratureArticle Details
PMID: 4879913 Published · ppublish English Journal Article

Diazomethane as the active agent in nitrosoguanidine mutagenesis and lethality.

Molecular & general genetics : MGG ·Vol. 101 ·No. 3 ·1968-05-03 ·Pages 191-202

Cerdá-Olmedo E, Hanawalt PC

Abstract

暂无摘要

MeSH Terms
Chromosomes/drug effects DNA Replication/drug effects Diazomethane/pharmacology Drug Resistance, Microbial Escherichia coli Genetics, Microbial Guanidines Hydrogen-Ion Concentration Mutagens/pharmacology Mutation/drug effects Nitroso Compounds/pharmacology
Chemicals
Guanidines Mutagens Nitroso Compounds Diazomethane
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Cerdá-Olmedo E
Hanawalt P C
References (23)
23 references, click to expand
  1. THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISM.
    Proc Natl Acad Sci U S A. 1964 Feb;51:226-31 PMID: 14124320
  2. [THE EFFECT OF CARCINOGENIC NITROSAMINE AND NITROSAMIDE ON THE ADENINE-6-45 REVERSE MUTATION SYSTEM OF SACCHAROMYCES CEREVISIAE].
    Z Vererbungsl. 1964 Apr 10;95:82-96 PMID: 14196023
  3. METHYLATION OF DEOXYRIBONUCLEIC ACID BY DIAZOMETHANE.
    Biochim Biophys Acta. 1964 Sep 11;91:59-66 PMID: 14227279
  4. Macromolecular action of nitrosoguanidine in Escherichia coli.
    Biochim Biophys Acta. 1967 Jul 18;142(2):450-64 PMID: 4861438
  5. The effect of cysteine on the metabolic changes produced by two carcinogenic Nnitrosodialklamines in rat liver.
    Cancer Res. 1962 Apr;22:339-51 PMID: 14474859
  6. Carcinogenic activity of N-methyl-N-nitroso-N'-nitroguanidine.
    Nature. 1966 Feb 12;209(5024):726-7 PMID: 5922140
  7. Radiation-induced mutations and their repair.
    Science. 1966 Jun 3;152(3727):1345-53 PMID: 5327888
  8. Screening data from the Cancer Chemotherapy National Service Center Screening Laboratories.
    Cancer Res. 1959 Apr;19(3 Part 2):31-193 PMID: 13638987
  9. Studies on the action of diazomethane on deoxyribonucleic acid. The action of diazomethane on deoxyribonucleosides.
    Biochim Biophys Acta. 1965 Jun 8;103(2):286-97 PMID: 5835618
  10. [On the production of subcutaneous sarcomas in rats. Carcinogenic effect of hydrazodicarbonic acid-bis-(methyl-nitrosamide), N-nitroso-N-n-butyl-urea, N-methyl-N-nitroso-nitroguanidine and N-nitroso-imidazolidone].
    Z Krebsforsch. 1966;68(1):87-102 PMID: 4228036
  11. On the methylation of dinucleoside phosphates with diazomethane.
    Biochim Biophys Acta. 1966 Aug 17;123(2):430-1 PMID: 5967259
  12. Repair of DNA damaged by N-methyl-N'-nitro-N-nitrosoguanidine in Escherichia coli.
    Mutat Res. 1967 May-Jun;4(3):369-71 PMID: 4861000
  13. Carcinogenic action of diazomethane and of nitroso-n-methyl urethane.
    Nature. 1960 Oct 29;188:420-1 PMID: 13748420
  14. Chemically induced mutations in Neurospora.
    Cold Spring Harb Symp Quant Biol. 1951;16:245-61 PMID: 14942743
  15. On a chemical degradation of deoxyribosenucleic acid.
    Biochim Biophys Acta. 1957 Jan;23(1):215-7 PMID: 13412710
  16. Chemical modification of viral RNA. VI. The action of N-methyl-N'-nitro-N-nitrosoguanidine.
    Proc Natl Acad Sci U S A. 1967 Jul;58(1):234-9 PMID: 5231604
  17. Carcinogenic action of N-methyl-N'-nitro-N-nitrosoguanidine.
    Nature. 1966 May 28;210(5039):962-3 PMID: 5960331
  18. A study of radiosensitive and radioresistant mutants of Escherichia coli strain B.
    J Gen Microbiol. 1961 Jan;24:1-14 PMID: 13714314
  19. Potential anticancer agents. XXXI. The relationship of chemical structure to antileukaemic activity with analogues of 1-methyl-3-nitro-1-nitrosoguanidine (NSC-9369).
    J Med Pharm Chem. 1960 Jun;2:299-333 PMID: 13831483
  20. Involvement of synthesis of RNA in thymineless death.
    Nature. 1963 Apr 20;198:286 PMID: 13952474
  21. A new chemical mutagen for bacteria, 1-methyl-3-nitro-1-nitrosoguanidine.
    Biochem Biophys Res Commun. 1960 Dec;3:575-7 PMID: 13766074
  22. Thymine deficiency and the normal DNA replication cycle. I.
    J Mol Biol. 1961 Apr;3:144-55 PMID: 13764647
  23. A new method of preparation of diazomethane.
    J Am Chem Soc. 1948 May;70(5):1974 PMID: 18861842
Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00271621
Published
1968-05-03
Pages
191-202
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00271621
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2