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PMID: 4868352 Published · ppublish English Journal Article

Mutants of Escherichia coli defective in ribonucleoside and deoxyribonucleoside catabolism.

Journal of bacteriology ·Vol. 95 ·No. 3 ·1968-03-00 ·Pages 1069-77

Karlström O

Abstract

From Escherichia coli B, mutants were prepared that lacked the enzymes adenosine deaminase, cytidine deaminase, and purine nucleoside phosphorylase. In each case, the mutant lacked enzyme activity for both ribonucleoside and deoxyribonucleoside. Mutants lacking purine nucleoside phosphorylase lost the capacity to cleave the nucleosides of adenine, guanine, and hypoxanthine.

MeSH Terms
Carbon Isotopes Chromatography, Paper Crosses, Genetic Escherichia coli/enzymology Genetics, Microbial Glucosyltransferases/metabolism Mutagens/pharmacology Mutation Nucleosides/metabolism Penicillins/pharmacology Spectrophotometry Thymine/metabolism
Chemicals
Carbon Isotopes Mutagens Nucleosides Penicillins Glucosyltransferases Thymine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Karlström O
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24 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.95.3.1069-1077.1968
Published
1968-03-00
Pages
1069-77
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC252133
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.95.3.1069-1077.1968 PMC Full Text View journal details
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