Arene oxides: a new aspect of drug metabolism.

Animals Benzene Derivatives/metabolism,toxicity Biotransformation Carcinogens Cell Transformation, Neoplastic Cells, Cultured Cricetinae Cytochrome P-450 Enzyme System/metabolism Ethers, Cyclic/metabolism Glutathione/metabolism Isomerism Liver/drug effects,metabolism Macromolecular Substances Mice Mutagens Naphthalenes/metabolism Oxepins/metabolism Oxides/metabolism Phenols/metabolism Polycyclic Compounds/metabolism,toxicity Protein Binding Rats

Benzene Derivatives Carcinogens Ethers, Cyclic Macromolecular Substances Mutagens Naphthalenes Oxepins Oxides Phenols Polycyclic Compounds Cytochrome P-450 Enzyme System Glutathione