Brain hyaluronidase: changes in activity during chick development.

Science (New York, N.Y.) ·Vol. 183 ·No. 4127 ·1974-03-01 ·Pages 862-4

Polansky JR, Toole BP, Gross J

Abstract

Development of embryonic chick brain is characterized by high levels of hyaluronidase activity and of hyaluronate, both of which decrease rapidly soon after the chick hatches. By analogy to other systems, it is proposed that the sequence of hyaluronate production and its enzymatic removal may have a developmental role in brain formation.

MeSH Terms

Animals Brain/embryology,enzymology,growth & development Brain Chemistry Chick Embryo Chickens Hyaluronic Acid/analysis Hyaluronoglucosaminidase/metabolism Hydrogen-Ion Concentration In Vitro Techniques Kinetics Nerve Tissue Proteins/analysis

Chemicals

Nerve Tissue Proteins Hyaluronic Acid Hyaluronoglucosaminidase

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Polansky J R

Toole B P

Gross J

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.183.4127.862

Published

1974-03-01

Pages

862-4

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.183.4127.862 View journal details

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