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PMID: 47202 Published · ppublish rus English Abstract Journal Article

[Linear differentiation of the human Y-chromosome].

Lineĭnaia differentsirovannost' Y-khromosomy cheloveka

Tsitologiia ·Vol. 17 ·No. 1 ·1975-01-00 ·Pages 19-23

Beniush VA, Oblapenko NG, Zakharov AF

Abstract

During the final 5.5th to 7th hr of the cycle in presence of BUdR, the human Y-chromosome was delayed in its mitotic condensation in the distal part of the long arm. This part was not homogeneous by the degree of the delay. The unevenly condensed Y-chromosome stained with quinacrine was brightly fluorescent in its stretched part. The fluorescence seemed to correlate with the degree of stretching. The distal part of the long arm was heavily labeled with H3-deoxycytidine thus demonstrating presence of late replicating DNA with GC-base pairs.

MeSH Terms
Adult Bromodeoxyuridine/pharmacology Child DNA Replication Deoxycytidine Fluorescence Humans Male Mitosis/drug effects Quinacrine Sex Chromosomes/ultrastructure Staining and Labeling Tritium
Chemicals
Deoxycytidine Tritium Bromodeoxyuridine Quinacrine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Beniush V A
Oblapenko N G
Zakharov A F
Article Info
Journal
Tsitologiia
Abbr.
Tsitologiia
ISSN
0041-3771
Published
1975-01-00
Pages
19-23
Language
rus
Region
Russia (Federation)
NLM ID
0417363
Subset
IM
External Links
PubMed source
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