Time course of early events in the action of glucocorticoids on rat thymus cells in vitro. Synthesis and turnover of a hypothetical cortisol-induced protein inhibition of glucose metabolism and of a presumed ribonucleic acid.

Adrenalectomy Animals Biological Transport Cells, Cultured Cycloheximide/pharmacology Dactinomycin/pharmacology Depression, Chemical Glucose/metabolism Hydrocortisone/pharmacology Male Protein Biosynthesis Proteins/pharmacology Puromycin/pharmacology RNA/biosynthesis Rats Stimulation, Chemical Temperature Thymus Gland/cytology,drug effects,metabolism Time Factors

Proteins Dactinomycin Puromycin RNA Cycloheximide Glucose Hydrocortisone