Endothelial cell membranes: polarity of particles as seen by freeze-fracturing.

Science (New York, N.Y.) ·Vol. 179 ·No. 4069 ·1973-01-12 ·Pages 190-2

Dempsey GP, Bullivant S, Watkins WB

Abstract

Freeze-fracturing shows particles within membranes. In plasma membranes of most cells the particles are more strongly bound to the inner half. In unfixed endothelial cells, this polarity is reversed. Glutaraldehyde fixation results in conventional polarity. The reverse polarity may be related to a mechanism for preferential fusion of pinocytotic vesicles with the plasma membrane.

MeSH Terms

Animals Cell Membrane Diaphragm/cytology Endothelium/cytology Epithelial Cells Female Freeze Etching Humans Kidney/cytology Liver/cytology Mice Microscopy, Electron Muscles/cytology Myocardium/cytology Pituitary Gland/cytology Placenta/cytology Rats

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Dempsey G P

Bullivant S

Watkins W B

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.179.4069.190

Published

1973-01-12

Pages

190-2

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.179.4069.190 View journal details

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Endothelial cell membranes: polarity of particles as seen by freeze-fracturing.

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