Symmetry and asymmetry in the mechanisms of hydrolysis by serine proteases and their thiol analogues.

Binding Sites Chymotrypsin/metabolism Cinnamates Dicyclohexylcarbodiimide Endopeptidases/metabolism Esters Hydrogen-Ion Concentration Kinetics Mercuribenzoates/pharmacology Nitrophenols Protein Binding Serine Structure-Activity Relationship Subtilisins/metabolism Sulfhydryl Compounds

Cinnamates Esters Mercuribenzoates Nitrophenols Sulfhydryl Compounds Serine Dicyclohexylcarbodiimide Endopeptidases Subtilisins Chymotrypsin