Malaria and erythrocyte glucose-6-phosphate dehydrogenase variants in West Africa.

The American journal of tropical medicine and hygiene ·Vol. 28 ·No. 4 ·1979-07-00 ·Pages 619-21

Bienzle U, Guggenmoos-Holzmann I, Luzzatto L

Abstract

In a clinical study, 702 Nigerian children aged 1-6 years were examined for malaria. Comparison of morbidity rates and parasitemia of patients with different glucose-6-phosphate dehydrogenase (G6PD) status provided evidence that in heterozygous females the gene for G6PD deficiency (GdA-/GdB) confers an advantage against malaria.

MeSH Terms

Child Child, Preschool Erythrocytes/enzymology,parasitology Female Genes Genetic Variation Genotype Glucosephosphate Dehydrogenase Deficiency/genetics Heterozygote Humans Infant Malaria/enzymology,genetics Male Nigeria Plasmodium

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Bienzle U

Guggenmoos-Holzmann I

Luzzatto L

Article Info

Journal

The American journal of tropical medicine and hygiene

Abbr.

Am J Trop Med Hyg

ISSN

0002-9637

Published

1979-07-00

Pages

619-21

Language

English

Region

United States

NLM ID

0370507

Subset

External Links

PubMed source View journal details

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Malaria and erythrocyte glucose-6-phosphate dehydrogenase variants in West Africa.

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