Is the notch locus of Drosophila melanogaster a tandem repeat? Correlation of the genetic map and complementation pattern of selected mutations.

Genetics ·Vol. 73 ·No. 3 ·1973-03-00 ·Pages 435-8

Foster GG

Abstract

Correlation of the complementation relationships between the Notch locus alleles fa(g), fa(no), Ax(59d) and nd, with their genetic map order, suggests a tandem repetition within the locus of functionally related sites. This observation is discussed in relation to two hypotheses: (1) that the Notch locus contains a tandem repeat of genetic material; and (2) that the tertiary structure of the Notch locus product has a spiral configuration.

MeSH Terms

Alleles Animals Chromosome Mapping Drosophila melanogaster Female Genetic Complementation Test Male Mutation Phenotype

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Foster G G

References (3)

3 references, click to expand

Temperature-sensitive mutations in Drosophila melanogaster. IV. A mutation affecting eye facet arrangement in a polarized manner.
Proc Natl Acad Sci U S A. 1970 Oct;67(2):738-45 PMID: 5002095
Pseudoallelism at the notch locus in drosophila.
Genetics. 1962 Jun;47:743-59 PMID: 14006076
A PRELIMINARY INVESTIGATION OF PSEUDOALLELISM AT THE NOTCH LOCUS OF Drosophila Melanogaster.
Proc Natl Acad Sci U S A. 1958 Mar;44(3):254-8 PMID: 16590184

Article Info

Journal

Genetics

Abbr.

Genetics

ISSN

0016-6731

DOI

10.1093/genetics/73.3.435

Published

1973-03-00

Pages

435-8

Language

English

Region

United States

NLM ID

0374636

PMCID

PMC1212903

Subset

External Links

PubMed source DOI: 10.1093/genetics/73.3.435 PMC Full Text View journal details

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Is the notch locus of Drosophila melanogaster a tandem repeat? Correlation of the genetic map and complementation pattern of selected mutations.

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