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PMID: 4632309 Published · ppublish English Journal Article

Mechanism for the regulation of cell division in Agmenellum.

Journal of bacteriology ·Vol. 113 ·No. 2 ·1973-02-00 ·Pages 1006-14

Ingram LO, Fisher WD

Abstract

We describe a nonlethal temperature-conditional mutant of Agmenellum quadruplicatum which allows dissociation of the processes of growth and cell division. With this system, evidence has been obtained for the regulation of one step in the process of cell division by a small effector molecule. The effector molecule is apparently released into the surrounding medium and can be obtained from lyophilized spent medium by extraction with 80% ethanol. The addition of this extract to serpentine filaments of the SN29 mutant strain stimulates cell division in these filaments and leads to the production of cells approximating normal dimensions within one generation time. The degree of stimulation of cell division is directly related to the amount of extract added. A general hypothesis is presented for the positive regulation of the initiation of cell wall and cell membrane invagination in this organism.

MeSH Terms
Bacteria/drug effects Cell Division/drug effects Cyanobacteria/growth & development Ethanol Microscopy, Phase-Contrast Mutagens Mutation Nitrosoguanidines Plant Extracts/pharmacology Plant Growth Regulators/pharmacology Solvents Spectrophotometry Temperature
Chemicals
Mutagens Nitrosoguanidines Plant Extracts Plant Growth Regulators Solvents Ethanol
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Ingram L O
Fisher W D
References (31)
31 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.113.2.1006-1014.1973
Published
1973-02-00
Pages
1006-14
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC285319
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.113.2.1006-1014.1973 PMC Full Text View journal details
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