Molecular approaches for designing antiviral and antitumor compounds.

Animals Antineoplastic Agents/chemical synthesis,pharmacology Antiviral Agents/chemical synthesis,pharmacology Binding Sites Cattle DNA DNA, Bacterial DNA-Directed RNA Polymerases/metabolism Daunorubicin/analysis,chemical synthesis Escherichia coli Leukocytes/drug effects,metabolism Moloney murine leukemia virus/drug effects,metabolism Nucleic Acid Denaturation Pyrroles/pharmacology Spectrophotometry Spectrophotometry, Ultraviolet Streptomyces Structure-Activity Relationship Templates, Genetic Thymus Gland Transcription, Genetic/drug effects

Antineoplastic Agents Antiviral Agents DNA, Bacterial Pyrroles DNA DNA-Directed RNA Polymerases Daunorubicin