Home LiteratureArticle Details
PMID: 4613593 Published · ppublish English Journal Article

Effects of glucose on the ultrastructure and insulin biosynthesis of isolated mouse pancreatic islets maintained in tissue culture.

Diabetologia ·Vol. 10 ·No. 6 ·1974-12-00 ·Pages 743-53

Andersson A, Westman J, Hellerström C

Abstract

暂无摘要

MeSH Terms
Adsorption Animals Cells, Cultured Chromatography, Gel Culture Techniques Glucose/pharmacology Histocytochemistry Insulin/biosynthesis,metabolism Insulin Antibodies Islets of Langerhans/drug effects,metabolism,ultrastructure Leucine/metabolism Male Mice Mice, Inbred Strains Microscopy, Electron Time Factors Tritium
Chemicals
Insulin Insulin Antibodies Tritium Leucine Glucose
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Andersson A
Westman J
Hellerström C
References (34)
34 references, click to expand
  1. Ultrastructure of monolayer cultures of pancreatic islet cells.
    Acta Diabetol Lat. 1970 Jul-Aug;7(4):557-61 passim PMID: 4930845
  2. Steroid diabetes in the guinea pig. Studies on islet-cell ultrastructure and regeneration.
    Diabetes. 1970 Mar;19(3):145-54 PMID: 4908764
  3. Mammalian pancreatic islet tissue in organ culture. II. Insulin contents of tissues and culture medium.
    Exp Cell Res. 1966 Feb;41(2):365-75 PMID: 5326038
  4. Monolayer cell culture of neonatal rat pancreas: an ultrastructural and biochemical study of functioning endocrine cells.
    J Ultrastruct Res. 1973 May;43(3):270-97 PMID: 4351013
  5. Insulin biosynthesis in the rat: demonstration of two proinsulins.
    Proc Natl Acad Sci U S A. 1969 Jan;62(1):278-85 PMID: 4890253
  6. [Organ culture of isolated islands of Langerhans from the obeses hyperglycemic mouse. Ultrastructural study].
    Biol Gastroenterol (Paris). 1973;6(3):205-15 PMID: 4600429
  7. Studies on the secretion of newly synthesized proinsulin and insulin from isolated rat islets of Langerhans.
    J Clin Invest. 1972 Jun;51(6):1476-85 PMID: 4336941
  8. Proinsulin and the biosynthesis of insulin.
    Recent Prog Horm Res. 1969;25:207-82 PMID: 4311938
  9. Morphological and biochemical studies of B cells of fetal rat endocrine pancreas in organ culture. Evidence for (pro) insulin biosynthesis.
    J Cell Biol. 1971 Sep;50(3):565-82 PMID: 5098861
  10. In vitro studies of the rate of proinsulin and insulin turnover in seven human insulinomas.
    Eur J Clin Invest. 1973 Sep;3(5):371-84 PMID: 4129637
  11. DISC ELECTROPHORESIS. II. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS.
    Ann N Y Acad Sci. 1964 Dec 28;121:404-27 PMID: 14240539
  12. Granulolysis in a cells of endocrine pancreas in spontaneous and experimental diabetes in animals.
    J Cell Biol. 1968 Aug;38(2):462-6 PMID: 5664218
  13. Effects of glucose on insulin biosynthesis in foetal and newborn rats.
    Horm Metab Res. 1973 Nov;5(6):410-5 PMID: 4588114
  14. The effect of glucose on insulin biosynthesis by isolated islets of Langerhans of the rat.
    Biochim Biophys Acta. 1970 Jun;208(3):404-13 PMID: 4918635
  15. The beta cell and its responses: summarizing remarks and some contributions from Geneva.
    Diabetes. 1972;21(2 Suppl):619-31 PMID: 4559922
  16. Long-term effects of glucose on insulin release and glucose oxidation by mouse pancreatic islets maintained in tissue culture.
    Biochem J. 1974 Jun;140(3):377-82 PMID: 4614795
  17. Insulin biosynthesis: evidence for a precursor.
    Science. 1967 Aug 11;157(3789):697-700 PMID: 4291105
  18. Monolayer cultures derived from neonatal hamster pancreas: stimulation of immunoreactive insulin secretion and biosynthesis.
    Proc Soc Exp Biol Med. 1973 Jun;143(2):335-9 PMID: 4708999
  19. A simple method for in vitro metabolic studies using small volumes of tissue and medium.
    Metabolism. 1963 Feb;12:143-7 PMID: 14031660
  20. Amino acid metabolism in mammalian cell cultures.
    Science. 1959 Aug 21;130(3373):432-7 PMID: 13675766
  21. Human pancreatic islet tumor cells maintained in vitro.
    Diabetologia. 1973 Aug;9(4):251-4 PMID: 4358419
  22. Metabolic characteristics of isolated pancreatic islets in tissue culture.
    Diabetes. 1972;21(2 Suppl):546-54 PMID: 4559919
  23. The isolation of insulin from a single cat pancreas.
    Biochim Biophys Acta. 1962 Sep 10;63:150-3 PMID: 14025543
  24. Tissue culture of A 2 cell-rich pancreatic islets isolated from guinea pigs.
    J Cell Biol. 1973 Apr;57(1):241-7 PMID: 4266245
  25. Evidence of an enzymatic degradation of insulin in blood in vitro.
    Eur J Biochem. 1971 Jan;18(2):201-6 PMID: 5541503
  26. Determination of total serum insulin (IRI) in insulin-treated diabetic patients.
    Diabetologia. 1972 Aug;8(4):260-6 PMID: 4673942
  27. Potassium ions and the secretion of insulin by islets of Langerhans incubated in vitro.
    Biochem J. 1968 Jun;108(1):17-24 PMID: 4297939
  28. Effect of glucose and tolbutamide on RNA synthesis in isolated islets of langerhans from rat pancreas.
    FEBS Lett. 1972 Mar;21(1):14-16 PMID: 11946463
  29. Protein measurement with the Folin phenol reagent.
    J Biol Chem. 1951 Nov;193(1):265-75 PMID: 14907713
  30. Long term (15 days) incubation of islets of Langerhans isolated from adult rats and mice.
    Lab Invest. 1972 Jul;27(1):53-61 PMID: 4556128
  31. Glucose and RNA synthesis in mammalian islets of Langerhans.
    Nature. 1967 Feb 11;213(5076):634-5 PMID: 5340263
  32. Role of ATP in the intracellular translocation of proinsulin and insulin in the rat pancreatic B cell.
    Nat New Biol. 1972 Jan 19;235(55):85-6 PMID: 4551334
  33. Studies on the conversion of proinsulin to insulin in the isolated islets of Langerhans in the rat.
    Can J Physiol Pharmacol. 1973 Mar;51(3):175-82 PMID: 4574455
  34. The Banting Memorial Lecture 1973: Islet differentiation, organ culture, and transplantation.
    Diabetes. 1973 Dec;22(12):877-912 PMID: 4128246
Article Info
Journal
Diabetologia
Abbr.
Diabetologia
ISSN
0012-186X
Published
1974-12-00
Pages
743-53
Language
English
Region
Germany
NLM ID
0006777
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com