Sensitivity to ampicillin and cephalothin of enzymes involved in wall peptide crosslinking in Escherichia coli K12, strain 44.

Acyltransferases/metabolism Ampicillin/pharmacology Bacterial Proteins/biosynthesis Carboxypeptidases/metabolism Cell Membrane/enzymology Cell Wall/metabolism Cephalothin/pharmacology Dose-Response Relationship, Drug Escherichia coli/cytology,drug effects,enzymology Lethal Dose 50 Microscopy, Phase-Contrast Mutation Nitrosoguanidines/pharmacology Penicillin G/pharmacology Penicillinase/metabolism Peptide Hydrolases/metabolism Rifampin/pharmacology Surface-Active Agents

Bacterial Proteins Nitrosoguanidines Surface-Active Agents Ampicillin Acyltransferases Carboxypeptidases Peptide Hydrolases Penicillinase Penicillin G Cephalothin Rifampin