Colicin E3 induced cleavage of 16S ribosomal ribonucleic acid; blocking effects of certain antibiotics.

Amino Sugars/pharmacology Anti-Bacterial Agents/pharmacology Autoradiography Colicins/antagonists & inhibitors,pharmacology Drug Resistance, Microbial Drug Stability Electrophoresis, Polyacrylamide Gel Erythromycin/pharmacology Escherichia coli/cytology,drug effects,growth & development,metabolism Gentamicins/pharmacology Inositol/pharmacology Phosphorus/metabolism Phosphorus Isotopes RNA, Bacterial/metabolism RNA, Ribosomal/metabolism Ribosomes/drug effects,metabolism Species Specificity Streptomycin/pharmacology Tetracycline/pharmacology

Amino Sugars Anti-Bacterial Agents Colicins Gentamicins Phosphorus Isotopes RNA, Bacterial RNA, Ribosomal Phosphorus Inositol Erythromycin Tetracycline Streptomycin