Curing of a killer factor in Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 69 ·No. 10 ·1972-10-00 ·Pages 2846-9

Fink GR, Styles CA

Abstract

Many standard laboratory stocks of yeast are able to kill other yeast strains. This property has not been generally recognized because killing is observed only at low pH and not at the pH of standard media. In all strains examined, the genetic determinant for the killer trait shows non-Mendelian inheritance. The segregation patterns of our killer strains indicate that this killer determinant may be different from the killer previously described. Treatment of a killer strain with cycloheximide, but not with ethidium bromide, converts it into a sensitive nonkiller.

MeSH Terms

Antibiosis Crosses, Genetic Culture Media Cycloheximide/pharmacology Ethidium/pharmacology Genetics, Microbial Genotype Hydrogen-Ion Concentration Meiosis Mitosis Nucleic Acids/metabolism Saccharomyces cerevisiae/drug effects,metabolism

Chemicals

Culture Media Nucleic Acids Cycloheximide Ethidium

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Fink G R

Styles C A

References (15)

15 references, click to expand

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Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.69.10.2846

Published

1972-10-00

Pages

2846-9

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC389659

Subset

External Links

PubMed source DOI: 10.1073/pnas.69.10.2846 PMC Full Text View journal details

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Curing of a killer factor in Saccharomyces cerevisiae.

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