Home LiteratureArticle Details
PMID: 4558508 Published · ppublish English Journal Article

Hypothesis: anencephaly and spina bifida are usually preventable by avoidance of a specific but unidentified substance present in certain potato tubers.

British journal of preventive & social medicine ·Vol. 26 ·No. 2 ·1972-05-00 ·Pages 67-88

Renwick JH

Abstract

暂无摘要

MeSH Terms
Africa Anencephaly/epidemiology,prevention & control Asia Europe Female Fungi Humans Infant, Newborn Ireland Male Nutritional Physiological Phenomena Plant Diseases Pregnancy Seasons Sex Factors Social Class Solanine South America Spinal Dysraphism/epidemiology,prevention & control United Kingdom United States Vegetables Water Softening
Chemicals
Solanine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Renwick J H
References (70)
70 references, click to expand
  1. Anencephalus, hydrocephalus, and spina bifida. Epidemiology, with special reference to a survey in Charleston, S.C.
    Arch Neurol. 1962 Nov;7:411-22 PMID: 14012311
  2. Incidence of congenital malformations in the regions of England and Wales.
    Br J Prev Soc Med. 1970 May;24(2):67-77 PMID: 4914434
  3. Pharmacology of solanine.
    Toxicol Appl Pharmacol. 1971 May;19(1):81-92 PMID: 4105761
  4. Anencephaly in Shiraz, Iran.
    Lancet. 1971 Jan 9;1(7689):82 PMID: 4099244
  5. Production of coumarins by Phytophthora infestans.
    Nature. 1966 Jun 11;210(5041):1165-6 PMID: 5964181
  6. Infant mortality from spina bifida, congenitalhydrocephalus, monstrosity, and congenital dseases of the cardiovascular system in England and Wales.
    Ann Hum Genet. 1971 Feb;34(3):295-305 PMID: 4926846
  7. ANENECEPHALY IN FRANCE.
    Am J Hum Genet. 1964 Sep;16:336-50 PMID: 14207549
  8. Ethnic differences in the prevalence of anencephaly and sina bifida in Boston, Massachusetts.
    N Engl J Med. 1967 Nov 23;277(21):1119-23 PMID: 4861562
  9. Toxic effects of potato sprouts and of solanine fed to pregnant rats.
    Proc Soc Exp Biol Med. 1961 Aug-Sep;107:807-9 PMID: 14456990
  10. The risk of recurrence after two children with central-nervous-system malformations.
    Lancet. 1967 Feb 11;1(7485):306-8 PMID: 4163511
  11. SEASONAL VARIATION IN CONGENITAL ABNORMALITIES. PRELIMINARY REPORT OF A SURVEY CONDUCTED BY THE RESEARCH COMMITTEE OF COUNCIL OF THE COLLEGE OF GENERAL PRACTITIONERS.
    Br J Prev Soc Med. 1964 Jan;18:1-7 PMID: 14113806
  12. Growth of differentiating testes and ovaries.
    Nature. 1969 Dec 27;224(5226):1323-5 PMID: 5359302
  13. Congenital malformations observed in 12146 births at the American University Hospital in Beirut.
    J Med Liban. 1966 May-Jun;19(3):113-21 PMID: 5962953
  14. Anencephalus: variation with maternal age, parity, social class and region in England, Scotland and Wales.
    Ann Hum Genet. 1970 Jul;34(1):31-8 PMID: 5476663
  15. Congenital malformations in Israel.
    Br J Prev Soc Med. 1967 Apr;21(2):66-77 PMID: 4382329
  16. SPINA BIFIDA IN LIVERPOOL.
    Dev Med Child Neurol. 1965 Jun;7:258-68 PMID: 14343222
  17. [On the incidence of congenital malformations of the central nervous system and the alimentary tract during the years 1950-61].
    Humangenetik. 1968;6(1):29-33 PMID: 5699891
  18. Observations on the results of pregnancies in women resident in Belfast. I. Data relating to all pregnancies ending in 1957.
    Ann Hum Genet. 1959 Dec;23:382-94 PMID: 13834547
  19. Congenital Abnormalities in Children Born in Alberta During 1961: A Survey and a Hypothesis.
    Can Med Assoc J. 1963 Jul 20;89(3):120-6 PMID: 20327618
  20. ANENCEPHALY IN LIVERPOOL.
    Dev Med Child Neurol. 1964 Jun;6:231-40 PMID: 14155181
  21. Changes in the incidence of neural-tube defects.
    Lancet. 1966 Oct 8;2(7467):791-3 PMID: 4162336
  22. Anencephaly and other congenital abnormalities. An epidemiological study in Northamptonshire.
    Br Med J. 1960 Jan 30;1(5169):309-15 PMID: 14433486
  23. [On the existence of seasonal variations in the incidence of anencephalia].
    Minerva Ginecol. 1965 Sep 30;17(18):928-34 PMID: 5880591
  24. [Anencephaly].
    Ned Tijdschr Geneeskd. 1971 Jun 19;115(25):1075-80 PMID: 5103974
  25. Congenital malformations and maternal diet.
    Australas Ann Med. 1961 Nov;10:268-74 PMID: 14486981
  26. The recent decline in prevalence of anencephaly and spina bifida.
    Am J Epidemiol. 1969 Feb;89(2):154-60 PMID: 4885535
  27. Anencephalus: a 23-year survey in a Sydney hospital.
    Med J Aust. 1967 Jan 21;1(3):104-6 PMID: 6018437
  28. CONGENITAL MALFORMATIONS. CLINICAL AND COMMUNITY CONSIDERATIONS.
    Am J Med Sci. 1965 Mar;249:316-44 PMID: 14273322
  29. Mortality from congenital malformations of the central nervous system in Norway, 1951-65. Life insurance companies' institute for medical statistics at the Oslo city hospitals, report no. 12.
    Br J Prev Soc Med. 1969 Feb;23(1):28-33 PMID: 4886413
  30. Anencephaly and spina bifida in the Province of Quebec.
    Can Med Assoc J. 1969 Apr 26;100(16):748-55 PMID: 4888983
  31. ANENCEPHALY. AN ANALYSIS OF ANENCEPHALIC BIRTHS AND A REPORT OF A CASE OF REPEATED ANENCEPHALY.
    Obstet Gynecol. 1963 Nov;22:657-61 PMID: 14082290
  32. Secular changes in the incidence of malformations of the central nervous system.
    Br J Soc Med. 1951 Oct;5(4):254-8 PMID: 14886593
  33. Major malformations of the central nervous system in Hungary.
    Br J Prev Soc Med. 1970 Nov;24(4):205-22 PMID: 4924869
  34. Spina bifida in Birmingham.
    Dev Med Child Neurol. 1967;:Suppl 13:14-22 PMID: 4860649
  35. Genetics of anencephaly and spina bifida?
    Lancet. 1968 Sep 14;2(7568):623-6 PMID: 4175169
  36. Comparisons of secular and seasonal variations in the incidence of anencephalus in Belfast and four Scottish cities, 1956-66.
    Br J Prev Soc Med. 1971 Feb;25(1):17-25 PMID: 5102515
  37. Congenital malformations of the central nervous system in Scotland.
    Br J Prev Soc Med. 1958 Jul;12(3):115-30 PMID: 13572782
  38. [Frequency of malformations at the University Women's Hospital Leipzig from 1941 to 1965. I. Frequency of malformations with special reference to gestosis].
    Zentralbl Gynakol. 1969 Jun 28;91(26):833-47 PMID: 4244043
  39. Congenital malformations in the newborn: a survey at the National Women's Hospital, 1964-67.
    N Z Med J. 1970 Feb;71(453):65-71 PMID: 4245879
  40. Seasonal incidence of congenital malformations of the central nervous system.
    Lancet. 1951 Jan 27;1(6648):192-6 PMID: 14795817
  41. THE FAMILY HISTORY OF SPINA BIFIDA CYSTICA.
    Pediatrics. 1965 Apr;35:589-95 PMID: 14269710
  42. Birth control and sex ratio.
    Lancet. 1970 Aug 22;2(7669):426 PMID: 4194739
  43. Declining incidence of central nervous system anomalies in New York State.
    Br J Prev Soc Med. 1962 Jul;16:153-8 PMID: 13898971
  44. Telencephalic remnants in simian and human anencephaly.
    Arch Pathol. 1971 Jun;91(6):529-36 PMID: 4995992
  45. Anencephaly. A 6 year study of 367 cases.
    Am J Obstet Gynecol. 1969 Apr 15;103(8):1154-9 PMID: 5774693
  46. Anencephaly in four consecutive pregnancies; report of a case.
    Fertil Steril. 1958 Jan-Feb;9(1):67-8 PMID: 13501272
  47. A small outbreak of solanine poisoning.
    Mon Bull Minist Health Public Health Lab Serv. 1959 Dec;18:207-10 PMID: 13845060
  48. A Swedish register of congenital malformations. Experience with continuous registration during 2 years with special reference to multiple malformations.
    Pediatrics. 1968 Apr;41(4):765-76 PMID: 5689407
  49. Anencephaly--a five year survey in Cork.
    J Ir Med Assoc. 1969 Sep;62(387):316-20 PMID: 5809833
  50. Malformations of central nervous system and softness of local water supplies.
    Br Med J. 1971 May 15;2(5758):357-61 PMID: 4930387
  51. The incidence of anencephaly in a polytypic population.
    Ann Hum Genet. 1959 Jul;23:279-88 PMID: 14444359
  52. REPORTED CONGENITAL MALFORMATIONS IN NEW YORK CITY, 1958-1959.
    Am J Public Health Nations Health. 1964 Sep;54:1489-506 PMID: 14218193
  53. A study of 137 cases of anencephaly.
    Br J Prev Soc Med. 1957 Oct;11(4):174-80 PMID: 13536294
  54. A study of major congenital defects in Japanese infants.
    Am J Hum Genet. 1958 Dec;10(4):398-445 PMID: 13606117
  55. THE FREQUENCY OF MALDEVELOPMENT IN MAN: THE NEED FOR IMPROVED STATISTICS.
    Am J Obstet Gynecol. 1964 Dec 1;90:SUPPL:994-1013 PMID: 14229523
  56. Anencephalus in Belfast. Incidence and secular and seasonal variations, 1950-66.
    Br J Prev Soc Med. 1970 May;24(2):78-88 PMID: 5431072
  57. Congenital malformations and perinatal mortality in Bombay.
    Am J Obstet Gynecol. 1967 Feb 1;97(3):400-6 PMID: 6016500
  58. Congenital malformations and environmental influences in pregnancy.
    Br J Prev Soc Med. 1969 Nov;23(4):218-25 PMID: 5355276
  59. Thalidomide syndrome in rhesus monkeys (Macaca mulatta).
    Folia Primatol (Basel). 1969;10(3):195-203 PMID: 5813580
  60. Anencephalus in Scotland.
    Br J Prev Soc Med. 1961 Jul;15:93-105 PMID: 14490889
  61. Anencephalus and water hardness in south-west Lancashire.
    Br J Prev Soc Med. 1971 Nov;25(4):217-9 PMID: 5160429
  62. Sex differences in the incidence of certain congenital malformations: a review of the literature and some new data.
    Teratology. 1971 Aug;4(3):277-86 PMID: 5568039
  63. Epidemiology of stillbirths and infant deaths due to congenital malformation.
    Lancet. 1958 Jun 21;1(7034):1304-6 PMID: 13550991
  64. Studies in spina bifida cystica. III. Seasonal variation in the frequency of spina bifida births.
    Br J Prev Soc Med. 1962 Jul;16:159-62 PMID: 13903150
  65. DISCORDANT ABNORMALITIES IN MONOZYGOTIC TWINS.
    J Pediatr. 1965 Jan;66:64-72 PMID: 14250057
  66. CONGENITAL MALFORMATIONS, ESPECIALLY ANENCEPHALUS, IN TAIWAN.
    Am J Obstet Gynecol. 1965 Mar 15;91:870-6 PMID: 14261045
  67. Maternal health and congenital defect; a prospective investigation.
    N Engl J Med. 1958 Apr 17;258(16):767-73 PMID: 13541657
  68. Major central nervous system malformations in South Wales. I. Incidence, local variations and geographical factors.
    Br J Prev Soc Med. 1968 Jul;22(3):146-60 PMID: 4874476
  69. Geographical variations in the mortality attributed to spina bifida and other congenital malformations.
    Br J Prev Soc Med. 1963 Jan;17:13-22 PMID: 13954287
  70. Anencephalus, spina bifida, and hydrocephalus incidence related to sex, race, and season of birth, and incidence in siblings.
    Br J Prev Soc Med. 1953 Oct;7(4):211-9 PMID: 13106264
Article Info
Journal
British journal of preventive & social medicine
Abbr.
Br J Prev Soc Med
ISSN
0007-1242
DOI
10.1136/jech.26.2.67
Published
1972-05-00
Pages
67-88
Language
English
Region
England
NLM ID
0372672
PMCID
PMC478703
Subset
IM
External Links
PubMed source DOI: 10.1136/jech.26.2.67 PMC Full Text
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2