Methyl 2-tetradecylglycidate, an orally effective hypoglycemic agent that inhibits long chain fatty acid oxidation selectively.

Animals Diabetes Mellitus, Experimental/metabolism Diaphragm/drug effects,metabolism Epoxy Compounds/pharmacology Ethers, Cyclic/pharmacology Fatty Acids/metabolism Hypoglycemic Agents/pharmacology Kidney Cortex/drug effects,metabolism Kinetics Oxidation-Reduction Palmitic Acids/metabolism Propionates/pharmacology Rats Structure-Activity Relationship

Epoxy Compounds Ethers, Cyclic Fatty Acids Hypoglycemic Agents Palmitic Acids Propionates methyl 2-tetradecylglycidate