Aging effects on the liver aldolase of rabbits.

The Biochemical journal ·Vol. 140 ·No. 2 ·1974-05-00 ·Pages 341-3

Anderson PJ

Abstract

A chemical method is used to determine the amount of aldolase sequence in rabbit livers. It is demonstrated that the aldolase sequences of the livers of young rabbits are more efficient catalytically than are those from the livers of old rabbits. The presence of altered residues in the aldolase sequences of old animals may account for these observations.

MeSH Terms

Aging Amino Acids Animals Autoanalysis Autoradiography Carbon Radioisotopes Chromatography, Gel Electrophoresis, Paper Electrophoresis, Polyacrylamide Gel Fructose-Bisphosphate Aldolase/metabolism Iodoacetates Liver/enzymology Methylation Rabbits

Chemicals

Amino Acids Carbon Radioisotopes Iodoacetates Fructose-Bisphosphate Aldolase

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Anderson P J

References (11)

11 references, click to expand

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Proc Natl Acad Sci U S A. 1973 Mar;70(3):909-13 PMID: 4197629
Structural relations in aldolases purified from rat liver and muscle and Novikoff hepatoma.
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Amino acid sequence homology in the active site of rabbit and sturgeon muscle aldolases.
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The reactivity of thiol groups and the subunit structure of aldolase.
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Amino acid sequence homology between muscle and liver aldolases.
FEBS Lett. 1971 Oct 15;18(1):59-63 PMID: 11946082
Inactive enzyme molecules in aging organisms. Nematode fructose-1,6-diphosphate aldolase.
Biochemistry. 1973 Apr 24;12(9):1743-50 PMID: 4699234
Error theory and ageing in human diploid fibroblasts.
Nature. 1972 Oct 6;239(5371):316-8 PMID: 12635218
Molecular and catalytic properties of aldolase C.
Biochemistry. 1969 Nov;8(11):4396-402 PMID: 4982047
A MICRO-BIURET METHOD FOR ESTIMATING PROTEINS.
Anal Biochem. 1964 Dec;9:401-10 PMID: 14239476
A comparative study of the structure of muscle fructose 1,6-diphosphate aldolases.
Eur J Biochem. 1969 Dec;11(3):503-9 PMID: 5368337
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Article Info

Journal

The Biochemical journal

Abbr.

Biochem J

ISSN

0264-6021

DOI

10.1042/bj1400341

Published

1974-05-00

Pages

341-3

Language

English

Region

England

NLM ID

2984726R

PMCID

PMC1168005

Subset

External Links

PubMed source DOI: 10.1042/bj1400341 PMC Full Text View journal details

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Aging effects on the liver aldolase of rabbits.

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