On the translational control of histone synthesis. Quantitation of biologically active histone mRNA from synchronized HeLa cells and its translation in different cell-free systems.

Animals Cell Division Cell-Free System Chromatography, DEAE-Cellulose Chromatography, Ion Exchange DNA/biosynthesis Dactinomycin/pharmacology Electrophoresis, Polyacrylamide Gel HeLa Cells/drug effects,metabolism Histones/biosynthesis Humans Hydroxyurea/pharmacology Mitosis/drug effects Peptide Chain Initiation, Translational Peptide Initiation Factors Polyribosomes/drug effects,metabolism Protein Biosynthesis/drug effects RNA, Messenger/metabolism RNA, Neoplasm/metabolism Rabbits Reticulocytes/metabolism Time Factors Ultrafiltration

Histones Peptide Initiation Factors RNA, Messenger RNA, Neoplasm Dactinomycin DNA Hydroxyurea