Inhibition of mitochondrial pyruvate transport by phenylpyruvate and alpha-ketoisocaproate.

Acetates/metabolism Animals Biological Transport, Active Brain/metabolism Caproates/pharmacology Carbon Radioisotopes Centrifugation, Density Gradient Cinnamates/pharmacology Cyanides/pharmacology Erythrocytes/drug effects,metabolism Humans Hydrazones/pharmacology Keto Acids/pharmacology Maple Syrup Urine Disease/physiopathology Mitochondria/drug effects,metabolism Mitochondria, Liver/drug effects,metabolism Mitochondria, Muscle/drug effects,metabolism Myocardium Phenylketonurias/physiopathology Phenylpyruvic Acids/pharmacology Pyruvates/blood,metabolism Rats Tritium

Acetates Caproates Carbon Radioisotopes Cinnamates Cyanides Hydrazones Keto Acids Phenylpyruvic Acids Pyruvates Tritium