Urinary D-glucaric acid excretion and acetanilide pharmacokinetics before and during diphenylhydantoin administration.

European journal of clinical pharmacology ·Vol. 7 ·No. 5 ·1974-08-23 ·Pages 387-91

Cunningham JL, Evans DA

Abstract

暂无摘要

MeSH Terms

Acetanilides/administration & dosage,blood Adipates/urine Administration, Oral Adult Analysis of Variance Colorimetry Creatinine/urine Drug Interactions Female Half-Life Humans Kinetics Male Metabolic Clearance Rate Oxidation-Reduction Phenytoin/administration & dosage,blood,pharmacology Sugar Acids/urine

Chemicals

Acetanilides Adipates Sugar Acids Phenytoin Creatinine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Cunningham J L

Evans D A

References (17)

17 references, click to expand

Clinical and electroencephalographic correlations with serum levels of diphenylhydanotin.
Arch Neurol. 1960 Jun;2:624-30 PMID: 13805571
The estimation of acetanilide and its metabolic products, aniline, N-acetyl p-aminophenol and p-amino-phenol, free and total conjugated, in biological fluids and tissues.
J Pharmacol Exp Ther. 1948 Sep;94(1):22-8 PMID: 18885610
Osteomalacia with long-term anticonvulsant therapy in epilepsy.
Br Med J. 1970 Oct 10;4(5727):69-72 PMID: 5312062
Effect of intensive occupational exposure to DDT on phenylbutazone and cortisol metabolism in human subjects.
Clin Pharmacol Ther. 1970 Sep-Oct;11(5):724-32 PMID: 5455634
Blood levels of drug at the equilibrium state after multiple dosing.
Nature. 1965 Sep 18;207(5003):1301-2 PMID: 5884654
Urinary D-glucaric-acid excretion as a test for hepatic enzyme induction in man.
Lancet. 1971 Mar 20;1(7699):572-5 PMID: 4100904
Plasma protein binding, plasma concentrations, and effects of diphenylhydantoin in man.
Ann N Y Acad Sci. 1971 Jul 6;179:723-8 PMID: 4998913
Clinical implications of enzyme induction.
Ann N Y Acad Sci. 1971 Jul 6;179:421-31 PMID: 5285387
Stimulatory effect of N-phenylbarbital (phetharbital) on cortisol hydroxylation in man.
Biochem Pharmacol. 1968 Apr;17(4):565-71 PMID: 5649552
Liver enzyme induction by anticonvulsant drugs, and its relationship to disturbed calcium and folic acid metabolism.
J Clin Pharmacol. 1973 Aug-Sep;13(8):337-42 PMID: 4199214
Genetic control of phenylbutazone metabolism in man.
Br Med J. 1970 Nov 7;4(5731):323-8 PMID: 5528753
Management of epilepsy with diphenylhydantoin sodium. Dosage regulation for problem patients.
JAMA. 1968 Mar 11;203(11):969-72 PMID: 5694319
Metabolism of d-glucuronolactone in mammalian systems. Identification of d-glucaric acid as a normal constituent of urine.
Biochem J. 1963 Jan;86(1):77-86 PMID: 16748985
Folate deficiency after anticonvulsant drugs: an effect of hepatic enzyme induction?
Br Med J. 1972 Jan 29;1(5795):297-9 PMID: 5008482
Imperfection: biochemical phobias and metabolic ambivalence.
Perspect Biol Med. 1959;2(4):473-517 PMID: 13667394
Genetic control of the phenobarbital-induced shortening of plasma antipyrine half-lives in man.
J Clin Invest. 1969 Dec;48(12):2202-9 PMID: 5389794
Treatment of Gilbert's syndrome with phenobarbitone.
Lancet. 1970 Jun 27;1(7661):1359-61 PMID: 4195058

Article Info

Journal

European journal of clinical pharmacology

Abbr.

Eur J Clin Pharmacol

ISSN

0031-6970

DOI

10.1007/BF00558212

Published

1974-08-23

Pages

387-91

Language

English

Region

Germany

NLM ID

1256165

Subset

External Links

PubMed source DOI: 10.1007/BF00558212 View journal details

Analysis Services

Urinary D-glucaric acid excretion and acetanilide pharmacokinetics before and during diphenylhydantoin administration.

Contact

WeChat Official Account