Studies on the immunosuppressive properties of asparaginase.

Immunology ·Vol. 21 ·No. 1 ·1971-07-00 ·Pages 137-50

Weksler ME, Weksler BB

Abstract

暂无摘要

MeSH Terms

Adrenalectomy Animals Antibody Formation/drug effects Asparaginase/pharmacology Asparagine/metabolism Cell Migration Inhibition DNA/biosynthesis Erythrocytes/immunology Graft Rejection/drug effects Graft vs Host Reaction/drug effects Hemagglutination Tests Humans Immunosuppressive Agents/pharmacology Injections, Intravenous Lectins Lymph Nodes/drug effects Lymphocyte Activation/drug effects Lymphocyte Transfusion Lymphocytes/drug effects,metabolism Lymphopenia/chemically induced Mice Sheep Skin Transplantation Spleen/drug effects,transplantation Thymidine/metabolism Thymus Gland/drug effects Transplantation, Homologous

Chemicals

Immunosuppressive Agents Lectins Asparagine DNA Asparaginase Thymidine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Weksler M E

Weksler B B

References (17)

17 references, click to expand

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L-asparaginase-induced immunosuppression: effects on antibody-forming cells and serum titers.
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Inhibition of glycoprotein synthesis in L5178Y mouse leukaemic cells by L-asparaginase in vitro.
Nature. 1970 May 30;226(5248):850-1 PMID: 5444625
A study of the graft-versus-host reaction in transplantation to embryos, F1 hybrids, and irradiated animals.
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Toxicity of L-asparaginase to resistant and susceptible lymphoma cells in vitro.
Proc Soc Exp Biol Med. 1967 Jun;125(2):598-601 PMID: 5339205
Immunosuppression by L-asparaginase.
Nature. 1969 Oct 18;224(5216):275-6 PMID: 5344608
L-asparaginase and blastogenesis.
Lancet. 1969 Feb 22;1(7591):423 PMID: 4179271
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Immunosuppressive activity of L-asparaginase in mice.
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The inhibition of lymphocyte blastogenesis by L-asparaginase.
Blood. 1970 Feb;35(2):250-62 PMID: 4905781
Studies on the mechanism of tumor inhibition by L-asparaginase. Effects of the enzyme on asparagine levels in the blood, normal tissues, and 6C3HED lymphomas of mice: differences in asparagine formation and utilization in asparaginase-sensitive and -resistant lymphoma cells.
J Exp Med. 1968 Jun 1;127(6):1055-72 PMID: 4871211
Neonatal thymectomy and hemolysin responses in inbred mice.
J Immunol. 1968 Aug;101(2):251-5 PMID: 5668025
EFFECT OF GLYCOSIDASES ON THE FATE OF TRANSFUSED LYMPHOCYTES.
Proc Natl Acad Sci U S A. 1964 Sep;52:750-5 PMID: 14212553
Immunosuppression by L-asparaginase.
Nature. 1970 Feb 7;225(5232):550-2 PMID: 4904264
The in vitro response to phytohemagglutinin of lyphoid cells from normal and neonatally thymectomized adult mice.
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Article Info

Journal

Immunology

Abbr.

Immunology

ISSN

0019-2805

Published

1971-07-00

Pages

137-50

Language

English

Region

England

NLM ID

0374672

PMCID

PMC1408088

Subset

External Links

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Studies on the immunosuppressive properties of asparaginase.

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