Cardio-selective beta-adrenoceptor blockade and the coronary circulation.

British journal of pharmacology ·Vol. 40 ·No. 3 ·1970-11-00 ·Pages 534-6

Adam KR, Boyles S, Scholfield PC

Abstract

After blockade of myocardial, but not coronary vascular beta-adrenoceptors by practolol, cardiac sympathetic stimulation or exogenously administered noradrenaline gave rise to coronary vasoconstriction, possibly due to stimulation of coronary alpha-adrenoceptors.

MeSH Terms

Acetanilides/pharmacology Adrenergic beta-Antagonists/pharmacology Amino Alcohols/pharmacology Animals Constriction Coronary Vessels/drug effects

Chemicals

Acetanilides Adrenergic beta-Antagonists Amino Alcohols

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Adam K R

Boyles S

Scholfield P C

References (5)

5 references, click to expand

Sympathetic control of coronary circulation.
Circ Res. 1967 Feb;20(2):262-71 PMID: 6016779
Effects of adrenaline and noradrenaline on coronary blood flow before and after beta-adrenergic blockade.
Br J Pharmacol Chemother. 1966 Mar;26(3):713-22 PMID: 4381204
Selective blockade of adrenoceptive beta receptors in the heart.
Br J Pharmacol Chemother. 1968 Jan;32(1):201-18 PMID: 4384337
Effects of a cardio-selective beta-adrenergic blocking agent on the heart and coronary circulation.
Cardiovasc Res. 1970 Apr;4(2):148-53 PMID: 4392942
The effect of "selective" beta-adrenoceptor blocking drugs on the myocardial circulation.
Br J Pharmacol. 1970 Jun;39(2):296-308 PMID: 4393214

Article Info

Journal

British journal of pharmacology

Abbr.

Br J Pharmacol

ISSN

0007-1188

DOI

10.1111/j.1476-5381.1970.tb10639.x

Published

1970-11-00

Pages

534-6

Language

English

Region

England

NLM ID

7502536

PMCID

PMC1703183

Subset

External Links

PubMed source DOI: 10.1111/j.1476-5381.1970.tb10639.x PMC Full Text View journal details

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Cardio-selective beta-adrenoceptor blockade and the coronary circulation.

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