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PMID: 4372400 Published · ppublish English Journal Article

Hemagglutination-inhibition: rapid assay for neuraminic acid-containing viruses.

Journal of virology ·Vol. 14 ·No. 5 ·1974-11-00 ·Pages 1307-9

Compans RW

Abstract

Influenza virus particles bind rapidly to vesicular stomatitis, Sindbis, or Rauscher murine leukemia virus particles, forming mixed aggregates demonstrable by electron microscopy. The normal hemagglutinating property of influenza virus is inhibited by these viruses, providing a rapid quantitative assay. Prior treatment with neuraminidase blocks the ability of other viruses to inhibit influenza virus hemagglutination.

MeSH Terms
Animals Binding Sites, Antibody Cell Line Cricetinae Evaluation Studies as Topic Glycoproteins/analysis Hemagglutination Inhibition Tests/methods Hemagglutinins, Viral Kidney Mice Microscopy, Electron Neuraminic Acids/analysis Orthomyxoviridae/immunology Rauscher Virus/analysis,isolation & purification Respirovirus/immunology Sindbis Virus/analysis,isolation & purification Vesicular stomatitis Indiana virus/analysis,isolation & purification Viral Proteins/analysis
Chemicals
Glycoproteins Hemagglutinins, Viral Neuraminic Acids Viral Proteins
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Compans R W
References (16)
16 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
Published
1974-11-00
Pages
1307-9
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC355650
Subset
IM
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