The fructose 1,6-diphosphatase-phosphofructokinase substrate cycle. A site of regulation of hepatic gluconeogenesis by glucagon.

Animals Carbon Radioisotopes Cyclic AMP/pharmacology Dose-Response Relationship, Drug Fructose-Bisphosphatase/metabolism Fructosephosphates/metabolism Glucagon/pharmacology Gluconeogenesis/drug effects Glucose/administration & dosage,metabolism Kinetics Lactates/metabolism Liver/cytology,drug effects,enzymology,metabolism Male Models, Chemical Multienzyme Complexes/metabolism Perfusion Phosphates/metabolism Phosphofructokinase-1/metabolism Pyruvates/metabolism Rats Structure-Activity Relationship Tritium

Carbon Radioisotopes Fructosephosphates Lactates Multienzyme Complexes Phosphates Pyruvates Tritium Glucagon Cyclic AMP Phosphofructokinase-1 Fructose-Bisphosphatase Glucose