Intracellular hydroxylation of non-helical protocollagen to form triple-helical procollagen and subsequent secretion of the molecule.

Anaerobiosis Animals Carbon Radioisotopes Chick Embryo Chromatography, Gel Chymotrypsin Collagen/biosynthesis,metabolism Cycloheximide/pharmacology Electrophoresis, Polyacrylamide Gel Hydroxyproline/biosynthesis Pepsin A Procollagen-Proline Dioxygenase/metabolism Protein Conformation Protein Precursors Pyridines/pharmacology Temperature Tendons/drug effects,metabolism Time Factors

Carbon Radioisotopes Protein Precursors Pyridines Collagen Cycloheximide Procollagen-Proline Dioxygenase Chymotrypsin Pepsin A Hydroxyproline