Two nucleic acid-dependent nucleoside triphosphate phosphohydrolases from vaccinia virus. Nucleotide substrate and polynucleotide cofactor specificities.

Adenosine Triphosphatases/metabolism Adenosine Triphosphate/metabolism Cytosine Nucleotides/metabolism DNA/pharmacology DNA Replication DNA, Bacterial/pharmacology DNA, Neoplasm/isolation & purification DNA, Viral/pharmacology Dactinomycin/pharmacology Guanosine Triphosphate/metabolism Nucleic Acid Denaturation Nucleic Acids/pharmacology Nucleotides/metabolism Phosphoric Monoester Hydrolases/antagonists & inhibitors,isolation & purification,metabolism Polynucleotides/pharmacology Structure-Activity Relationship Thymine Nucleotides/metabolism Transcription, Genetic Tritium Uracil Nucleotides/metabolism Vaccinia virus/enzymology

Cytosine Nucleotides DNA, Bacterial DNA, Neoplasm DNA, Viral Nucleic Acids Nucleotides Polynucleotides Thymine Nucleotides Uracil Nucleotides Tritium Dactinomycin Guanosine Triphosphate Adenosine Triphosphate DNA Phosphoric Monoester Hydrolases Adenosine Triphosphatases