Human cytomegalovirus. II. Lack of relatedness to DNA of herpes simples I and II, Epstein-Barr virus, and nonhuman strains of cytomegalovirus.

Journal of virology ·Vol. 13 ·No. 3 ·1974-03-00 ·Pages 642-5

Huang ES, Pagano JS

Abstract

The purified DNA of human cytomegalovirus, radiolabeled in vitro, was examined for homology to Epstein-Barr virus, herpes simplex type I and II, and simian and murine cytomegalovirus DNA by DNA-DNA reassociation kinetics analyses with the S1 enzyme differential digestion technique. Cross-matching of the DNAs showed no relatedness or less than 5% detectable homology.

MeSH Terms

Aspergillus/enzymology Cytomegalovirus/analysis DNA, Viral/analysis Endonucleases Herpesvirus 4, Human/analysis Nucleic Acid Denaturation Nucleic Acid Hybridization Nucleic Acid Renaturation Simplexvirus/analysis

Chemicals

DNA, Viral Endonucleases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Huang E S

Pagano J S

References (14)

14 references, click to expand

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Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.13.3.642-645.1974

Published

1974-03-00

Pages

642-5

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC355349

Subset

External Links

PubMed source DOI: 10.1128/JVI.13.3.642-645.1974 PMC Full Text View journal details

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Human cytomegalovirus. II. Lack of relatedness to DNA of herpes simples I and II, Epstein-Barr virus, and nonhuman strains of cytomegalovirus.

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