The enhancement by caffeine of alkylation-induced cell death, mutations and chromosomal aberrations in Chinese hamster cells, as a result of inhibition of post-replication DNA repair.

Mutation research ·Vol. 26 ·No. 2 ·1974-04-00 ·Pages 129-43

Roberts JJ, Sturrock JE, Ward KN

Abstract

暂无摘要

MeSH Terms

Alkylation Animals Azaguanine Caffeine/pharmacology Cell Division/drug effects Cell Survival/drug effects Cells, Cultured Chromosome Aberrations/drug effects Cricetinae DNA/biosynthesis DNA Repair/drug effects DNA Replication HeLa Cells Humans Lung Mesylates/pharmacology Mustard Compounds/pharmacology Mutation/drug effects Nitrosourea Compounds/pharmacology Sulfur/pharmacology Thymidine/metabolism Tritium

Chemicals

Mesylates Mustard Compounds Nitrosourea Compounds Tritium Caffeine Sulfur DNA Azaguanine Thymidine

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Roberts J J

Sturrock J E

Ward K N

Article Info

Journal

Mutation research

Abbr.

Mutat Res

ISSN

0027-5107

DOI

10.1016/s0027-5107(74)80043-6

Published

1974-04-00

Pages

129-43

Language

English

Region

Netherlands

NLM ID

0400763

Subset

External Links

PubMed source DOI: 10.1016/s0027-5107(74)80043-6 View journal details

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The enhancement by caffeine of alkylation-induced cell death, mutations and chromosomal aberrations in Chinese hamster cells, as a result of inhibition of post-replication DNA repair.

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