Homeoviscous adaptation--a homeostatic process that regulates the viscosity of membrane lipids in Escherichia coli.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 71 ·No. 2 ·1974-02-00 ·Pages 522-5

Sinensky M

Abstract

E. coli incorporates increasing proportions of saturated and long-chain fatty acids into phospholipids as growth temperature is increased. It was found that this compositional variation results in the biosynthesis of phospholipids that have identical viscosities at the temperature of growth of the cells. This "homeoviscous adaptation" can also be observed in E. coli membrane preparations. Viscosities were determined by use of the electron spin resonance spin-label technique.

MeSH Terms

Cell Membrane/metabolism Electron Spin Resonance Spectroscopy Escherichia coli/growth & development,metabolism Fatty Acids/metabolism Homeostasis Phospholipids/biosynthesis Spin Labels Temperature Viscosity

Chemicals

Fatty Acids Phospholipids Spin Labels

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Sinensky M

References (13)

13 references, click to expand

Spin-labeled biomolecules.
Proc Natl Acad Sci U S A. 1965 Oct;54(4):1010-7 PMID: 5219813
EFFECT OF TEMPERATURE ON THE COMPOSITION OF FATTY ACIDS IN ESCHERICHIA COLI.
J Bacteriol. 1962 Dec;84(6):1260-7 PMID: 16561982
A spin-labeled lipid for probing biological membranes.
Chem Phys Lipids. 1969 Sep;3(3):245-53 PMID: 4310541
Fatty acid degradation in Escherichia coli. An inducible acyl-CoA synthetase, the mapping of old-mutations, and the isolation of regulatory mutants.
Eur J Biochem. 1969 Feb;7(4):559-74 PMID: 4887396
Spin-labeled transfer RNA.
Proc Natl Acad Sci U S A. 1969 Apr;62(4):1195-202 PMID: 4307874
Lipid spin labels in lecithin multilayers. A study of motion along fatty acid chains.
J Mol Biol. 1971 Jul 14;59(1):77-98 PMID: 4326898
Molecular motion in spin-labeled phospholipids and membranes.
J Am Chem Soc. 1971 Jan 27;93(2):314-26 PMID: 5541516
Changes in the chemical and the barrier properties of the membrane lipids of E. coli by variation of the temperature of growth.
Chem Phys Lipids. 1969 Dec;3(4):413-7 PMID: 4905515
Hybridization between Escherichia coli and Shigella.
J Bacteriol. 1957 Oct;74(4):461-76 PMID: 13475269
Purification and properties of C 55 -isoprenoid alcohol phosphokinase from Staphylococcus aureus.
J Biol Chem. 1972 Aug 25;247(16):5123-31 PMID: 5057461
A rapid method of total lipid extraction and purification.
Can J Biochem Physiol. 1959 Aug;37(8):911-7 PMID: 13671378
Temperature control of phospholipid biosynthesis in Escherichia coli.
J Bacteriol. 1971 May;106(2):449-55 PMID: 4324806
Lateral phase separations in membrane lipids and the mechanism of sugar transport in Escherichia coli.
Proc Natl Acad Sci U S A. 1973 Aug;70(8):2271-5 PMID: 4365369

Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.71.2.522

Published

1974-02-00

Pages

522-5

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC388039

Subset

External Links

PubMed source DOI: 10.1073/pnas.71.2.522 PMC Full Text View journal details

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Homeoviscous adaptation--a homeostatic process that regulates the viscosity of membrane lipids in Escherichia coli.

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