The mechanism of action of adrenocroticotropic hormone. The role of mitochondrial cholesterol accumulation in the regulation of steroidogenesis.

Adrenal Glands/cytology,drug effects,metabolism Adrenocorticotropic Hormone/pharmacology Aminoglutethimide/pharmacology Animals Bucladesine/pharmacology Cholesterol/metabolism Chromatography, Gas Cyclic AMP/pharmacology Cycloheximide/pharmacology Cytosol/metabolism Hypophysectomy Male Microscopy, Electron Mitochondria/drug effects,metabolism Pituitary Gland/physiology Pregnenolone/biosynthesis Rats Subcellular Fractions/drug effects,metabolism Swine Time Factors

Aminoglutethimide Bucladesine Pregnenolone Adrenocorticotropic Hormone Cholesterol Cycloheximide Cyclic AMP