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PMID: 4358165 Published · ppublish English Journal Article

Morphogenesis of poliovirus 3. Formation of provirion in cell-free extracts.

Journal of virology ·Vol. 12 ·No. 5 ·1973-11-00 ·Pages 1181-3

Fernandez-Tomas CB, Guttman N, Baltimore D

Abstract

Formation of an apparent virion precursor, the provirion, can be demonstrated in cytoplasmic extracts of poliovirus-infected HeLa cells.

MeSH Terms
Carbon Radioisotopes Cell-Free System Centrifugation, Density Gradient Dactinomycin/pharmacology HeLa Cells Humans Leucine/metabolism Poliovirus/drug effects RNA, Viral/analysis Sucrose Time Factors Tritium Uridine/metabolism Viral Proteins/analysis
Chemicals
Carbon Radioisotopes RNA, Viral Viral Proteins Tritium Dactinomycin Sucrose Leucine Uridine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Fernandez-Tomas C B
Guttman N
Baltimore D
References (3)
3 references, click to expand
  1. In vitro assembly of poliovirus-related particles.
    Virology. 1968 Jun;35(2):216-26 PMID: 4299274
  2. In vitro assembly of poliovirus. II. Evidence for the self-assembly of 14 S particles into empty capsids.
    Virology. 1971 May;44(2):307-16 PMID: 4105254
  3. Morphogenesis of poliovirus. II. Demonstration of a new intermediate, the proviron.
    J Virol. 1973 Nov;12(5):1122-30 PMID: 4358164
Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
Published
1973-11-00
Pages
1181-3
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC356751
Subset
IM
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