Complement-fixing antigens produced by varicella-zoster virus in tissue culture.

Applied microbiology ·Vol. 26 ·No. 3 ·1973-09-00 ·Pages 410-6

Martin ML, Palmer EL

Abstract

The complement-fixing antigens present in tissue cultures infected with varicella-zoster virus were separated into four components. There were (i) a cell-free soluble antigen, (ii) a cell-associated soluble antigen, (iii) a cell membrane-associated antigen, and (iv) a virion antigen. All four antigens were reactive with sera from patients with varicella or zoster, and about 90% of the total complement-fixing activity was found to be nonvirion associated.

MeSH Terms

Antibodies, Viral/analysis Antigens/analysis Antigens, Viral/analysis Cell Membrane/immunology Centrifugation, Density Gradient Chickenpox/blood Complement Fixation Tests Culture Techniques Fibroblasts Herpes Zoster/blood Herpesvirus 3, Human/immunology Humans Immune Sera Microscopy, Electron Protein Binding Solubility

Chemicals

Antibodies, Viral Antigens Antigens, Viral Immune Sera

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Martin M L

Palmer E L

References (5)

5 references, click to expand

Production of specific varicella antiserum.
Appl Microbiol. 1968 Jan;16(1):160-2 PMID: 4295177
Viscosity-density gradient for purification of foot-and-mouth disease virus.
Arch Gesamte Virusforsch. 1972;36(1):141-6 PMID: 4335020
Immunological specificity of the glycoproteins of herpes simplex virus subtypes 1 and 2.
J Gen Virol. 1972 Oct;17(1):31-48 PMID: 4343529
The soluble antigens of varicella-zoster virus produced in tissue culture.
J Hyg (Lond). 1961 Jun;59:249-58 PMID: 13691671
A COMPLEMENT-FIXING ANTIGEN FOR VARICELLA-ZOSTER DERIVED FROM INFECTED CULTURES OF HUMAN FETAL DIPLOID CELLS.
Proc Soc Exp Biol Med. 1964 May;116:144-9 PMID: 14200088

Article Info

Journal

Applied microbiology

Abbr.

Appl Microbiol

ISSN

0003-6919

DOI

10.1128/am.26.3.410-413.1973

Published

1973-09-00

Pages

410-6

Language

English

Region

United States

NLM ID

7605802

PMCID

PMC379801

Subset

External Links

PubMed source DOI: 10.1128/am.26.3.410-413.1973 PMC Full Text

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Complement-fixing antigens produced by varicella-zoster virus in tissue culture.

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