Isolation of a neurotropic type C virus.

Science (New York, N.Y.) ·Vol. 181 ·No. 4103 ·1973-09-07 ·Pages 945-7

Officer JE, Tecson N, Estes JD, Fontanilla E, Rongey RW, Gardner MB

Abstract

A neurogenic paralysis of the lower limb can be induced and serially transmitted in mice by a nontransforming type C virus strain that originated in an embryo of a wild mouse. The virus exerted a neurotropic effect on the anterior horn neurons.

MeSH Terms

Animals Antigens, Viral/analysis Brain/immunology Cells, Cultured Complement Fixation Tests Embryo, Mammalian/microbiology Hindlimb Lymphoma/etiology Mice Muscles/immunology Oncogenic Viruses/isolation & purification Paralysis/etiology,immunology RNA Viruses/isolation & purification Retroviridae/growth & development,immunology,isolation & purification Spinal Cord/immunology Spleen/immunology

Chemicals

Antigens, Viral

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Officer J E

Tecson N

Estes J D

Fontanilla E

Rongey R W

Gardner M B

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.181.4103.945

Published

1973-09-07

Pages

945-7

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.181.4103.945 View journal details

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Isolation of a neurotropic type C virus.

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