Cyclic AMP as a mediator of the relaxing action of papaverine, nitroglycerine, diazoxide and hydralazine in intestinal and vascular smooth muscle.

Adenosine Triphosphate/analysis Animals Arteries/drug effects Calcium/physiology Cattle Colon/drug effects Cyclic AMP/analysis,physiology Diazoxide/pharmacology Hydralazine/pharmacology In Vitro Techniques Muscle, Smooth/drug effects Nitroglycerin/pharmacology Papaverine/pharmacology Phosphocreatine/analysis Phosphoric Diester Hydrolases/metabolism Rabbits Stimulation, Chemical Subcellular Fractions/drug effects Time Factors

Phosphocreatine Hydralazine Adenosine Triphosphate Papaverine Cyclic AMP Phosphoric Diester Hydrolases Nitroglycerin Diazoxide Calcium