Glucagon stimulation of adenylate cyclase sulfhydryl reactivity. Evidence for hormone-induced conformational changes.

Adenosine Triphosphate Adenylyl Cyclase Inhibitors Adenylyl Cyclases/metabolism Amides/pharmacology Animals Binding Sites Carbon Isotopes Cyclic AMP Drug Synergism Glucagon/pharmacology Iodoacetates/pharmacology Liver/drug effects,enzymology Membranes/drug effects,enzymology Protein Conformation Rats Receptors, Cell Surface Sulfhydryl Compounds/metabolism Tritium

Adenylyl Cyclase Inhibitors Amides Carbon Isotopes Iodoacetates Receptors, Cell Surface Sulfhydryl Compounds Tritium Adenosine Triphosphate Glucagon Cyclic AMP Adenylyl Cyclases