Leukemia virus activation during homograft rejection.

Science (New York, N.Y.) ·Vol. 180 ·No. 4085 ·1973-05-04 ·Pages 500-2

Hirsch MS, Ellis DA, Black PH, Monaco AP, Wood ML

Abstract

Activation of murine leukemia viruses, as detected by the mixed culture cytopathogenicity (XC) assay, followed the transplantation of A/J skin onto immunosuppressed BALB/c mice. Virus was found in most of the mice receiving both skin grafts and antilymphocyte serum, but not in animals receiving either the serum alone, skin graft alone, or no treatment.

MeSH Terms

Animals Antilymphocyte Serum Cytopathogenic Effect, Viral Graft Rejection Immunosuppression Therapy Immunosuppressive Agents Leukemia Virus, Murine/growth & development Mice Mice, Inbred A Mice, Inbred BALB C Skin Transplantation Spleen/microbiology Transplantation, Homologous

Chemicals

Antilymphocyte Serum Immunosuppressive Agents

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Hirsch M S

Ellis D A

Black P H

Monaco A P

Wood M L

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.180.4085.500

Published

1973-05-04

Pages

500-2

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.180.4085.500 View journal details

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