Exocytosis in the adrenal medulla demonstrated by freeze-etching.

Science (New York, N.Y.) ·Vol. 179 ·No. 4068 ·1973-01-05 ·Pages 79-82

Smith U, Smith DS, Winkler H, Ryan JW

Abstract

Replicas of fractured chromaffin cells are indicative of a range of activities thought to characterize exocytosis, including attachment of secretory vesicles to the plasma membrane, fusion, extrusion of contents, and membrane retrieval. Exocytosis sites are abundant on stimulated cells but are infrequent when calcium is omitted from the system.

MeSH Terms

Adrenal Medulla/cytology,drug effects Angiotensin II/pharmacology Animals Bradykinin/pharmacology Calcium Catecholamines/metabolism Cell Membrane Cells/metabolism Cricetinae Exocytosis/drug effects Extracellular Space Freeze Etching Microscopy, Electron Perfusion

Chemicals

Catecholamines Angiotensin II Bradykinin Calcium

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Smith U

Smith D S

Winkler H

Ryan J W

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.179.4068.79

Published

1973-01-05

Pages

79-82

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.179.4068.79 View journal details

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Exocytosis in the adrenal medulla demonstrated by freeze-etching.

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