Effect of colchicine, colcemid, and vinblastine on the agglutination, by concanavalin A, of transformed cells.

Science (New York, N.Y.) ·Vol. 178 ·No. 4063 ·1972-11-24 ·Pages 867-8

Yin HH, Ukena TE, Berlin RD

Abstract

The sensitivity of transformed 3T3 fibroblasts to agglutination by concanavalin A is reduced by alkaloids that bind specifically to protein subunits of microtubules.

MeSH Terms

Agglutination/drug effects Animals Cell Line Cell Transformation, Neoplastic Colchicine/pharmacology Concanavalin A/antagonists & inhibitors Erythrocytes/immunology Hemadsorption Hemagglutination Lectins/antagonists & inhibitors Mice Simian virus 40 Vinblastine/pharmacology

Chemicals

Lectins Concanavalin A Vinblastine Colchicine

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Yin H H

Ukena T E

Berlin R D

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.178.4063.867

Published

1972-11-24

Pages

867-8

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.178.4063.867 View journal details

Analysis Services

Effect of colchicine, colcemid, and vinblastine on the agglutination, by concanavalin A, of transformed cells.

Contact

WeChat Official Account