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PMID: 4339509 Published · ppublish English Journal Article

Equine abortion (herpes) virus: strain differences in susceptibility to inactivation by dithiothreitol.

Applied microbiology ·Vol. 23 ·No. 6 ·1972-06-00 ·Pages 1121-4

Klingeborn B, Dinter Z

Abstract

The infectivity of equine abortion (herpes) virus (EAV) was inactivated by treatment with reduced dithiothreitol (DTT). According to their susceptibility to DTT, the EAV strains could be divided into three groups. The vaccine strain RAC-H (419) proved to be more resistant to DTT than all of the other 14 strains tested. The hemagglutinin of EAV was also inactivated by DTT; no strain differences were observed in this respect.

MeSH Terms
Abortion, Veterinary Animals Cattle Cell Line/microbiology Clone Cells Dithiothreitol/pharmacology Drug Resistance, Microbial Female Hemagglutination Tests Hemagglutinins, Viral/antagonists & inhibitors Herpesviridae/drug effects,growth & development,immunology Herpesviridae Infections/veterinary Horse Diseases Horses Kidney L Cells/microbiology Lung Mice Orthomyxoviridae Infections/veterinary Pregnancy Swine Viral Vaccines Virus Cultivation
Chemicals
Hemagglutinins, Viral Viral Vaccines Dithiothreitol
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Klingeborn B
Dinter Z
References (10)
10 references, click to expand
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    J Virol. 1968 Dec;2(12):1482-4 PMID: 4315605
  3. Differentiation of equine herpesvirus type I strains by a plaque marker. Brief report.
    Arch Gesamte Virusforsch. 1970;32(2):283-5 PMID: 5533700
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    Virology. 1971 Jul;45(1):91-100 PMID: 4106985
  5. Equine herpesvirus type 1: the L- character in two of forty-three field isolates. Brief report.
    Arch Gesamte Virusforsch. 1972;36(3):391-3 PMID: 5063121
  6. Equine abortion (herpes) virus: purification and concentration of enveloped and deenveloped virus and envelope material by density gradient centrifugation in colloidal silica.
    Virology. 1972 May;48(2):618-23 PMID: 4337037
  7. DITHIOTHREITOL, A NEW PROTECTIVE REAGENT FOR SH GROUPS.
    Biochemistry. 1964 Apr;3:480-2 PMID: 14192894
  8. Agglutination of horse erythrocytes by tissue extracts from hamsters infected with equine abortion virus.
    Am J Vet Res. 1956 Apr;17(63):267-70 PMID: 13302651
  9. TRANSFORMATION OF BOVINE CELLS IN VITRO AFTER INOCULATION OF SIMIAN VIRUS 40 OR ITS NUCLEIC ACID.
    Exp Cell Res. 1965 Feb;37:452-9 PMID: 14298956
  10. Role of hydrogen and disulfide bonds in polyoma capsid structure.
    Virology. 1968 Mar;34(3):481-91 PMID: 4297163
Article Info
Journal
Applied microbiology
Abbr.
Appl Microbiol
ISSN
0003-6919
DOI
10.1128/am.23.6.1121-1124.1972
Published
1972-06-00
Pages
1121-4
Language
English
Region
United States
NLM ID
7605802
PMCID
PMC380517
Subset
IM
External Links
PubMed source DOI: 10.1128/am.23.6.1121-1124.1972 PMC Full Text
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