Cell cycle-dependent activation of rous sarcoma virus-infected stationary chicken cells: avian leukosis virus group-specific antigens and ribonucleic acid.

Journal of virology ·Vol. 10 ·No. 1 ·1972-07-00 ·Pages 82-7

Humphries EH, Temin HM

Abstract

Stationary chicken embryo fibroblasts exposed to Rous sarcoma virus (RSV) remained stably infected for at least 5 days, but they did not release infectious virus or become transformed until after cell division. These infected stationary cells did not contain avian leukosis virus group-specific antigens or ribonucleic acid (RNA) hybridizable to deoxyribonucleic acid (DNA) made by the RSV endogenous RNA-directed DNA polymerase activity.

MeSH Terms

Animals Antigens/analysis Antigens, Viral/analysis Avian Leukosis Virus/immunology Avian Sarcoma Viruses/growth & development Cell Division Cells, Cultured/analysis,immunology,microbiology Centrifugation, Density Gradient Chick Embryo Complement Fixation Tests Cytosine Nucleotides/metabolism DNA Nucleotidyltransferases/metabolism DNA, Viral/biosynthesis Fibroblasts Fluorescent Antibody Technique Immune Sera Nucleic Acid Hybridization RNA, Viral/analysis Rabbits/immunology Thymine Nucleotides/metabolism Tritium Virus Replication

Chemicals

Antigens Antigens, Viral Cytosine Nucleotides DNA, Viral Immune Sera RNA, Viral Thymine Nucleotides Tritium DNA Nucleotidyltransferases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Humphries E H

Temin H M

References (16)

16 references, click to expand

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Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.10.1.82-87.1972

Published

1972-07-00

Pages

82-7

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC356428

Subset

External Links

PubMed source DOI: 10.1128/JVI.10.1.82-87.1972 PMC Full Text View journal details

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Cell cycle-dependent activation of rous sarcoma virus-infected stationary chicken cells: avian leukosis virus group-specific antigens and ribonucleic acid.

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