Reversible inhibition by histidinol of protein synthesis in human cells at the activation of histidine.

Adenosine Triphosphate/metabolism Amino Acyl-tRNA Synthetases/antagonists & inhibitors Amino Alcohols/pharmacology Biological Transport Carbon Isotopes Culture Media Cytoplasm/enzymology Diphosphates/metabolism HeLa Cells/drug effects,enzymology,metabolism Histidine/metabolism Humans Imidazoles/metabolism Kinetics Leucine/metabolism Neoplasm Proteins/biosynthesis Phosphorus Isotopes Protein Binding Time Factors Transfer RNA Aminoacylation/drug effects

Amino Alcohols Carbon Isotopes Culture Media Diphosphates Imidazoles Neoplasm Proteins Phosphorus Isotopes Histidine Adenosine Triphosphate Amino Acyl-tRNA Synthetases Leucine